Randomized Comparison of Low Dose versus High Dose Interferon-alpha in Chronic Myeloid Leukemia

Hanneke C. Kluin-Nelemans, Georgina Buck, Saskia le Cessie, Sue Richards, H. Berna Beverloo, J.H. Frederik Falkenburg, Tim Littlewood, Petra Muus, David Bareford, Hans van der Lelie, Anthony R Green, Klaas J. Roozendaal, Alison E Milne, Claire S. Chapman and Patricia Shepherd on behalf of the CML Working Group of the NCRI Adult Leukaemia Working Party and the HOVON trials group. Dept. Hematology, University Medical Center Groningen, The Netherlands; Clinical Trial Service Unit, Oxford, UK; Dept. of Medical Statistics, Leiden University Medical Center, The Netherlands; Dept Clinical Genetics, Erasmus Medical Center, Rotterdam, The Netherlands; Dept Haematology, Leiden University Medical Center, Leiden, The Netherlands; Dept Hematology, The John Radcliffe Hospital, Oxford, UK; Dept Hematology, University Medical Center Nijmegen, The Netherlands; City Hospital NHS Trust, Birmingham, UK; Dept Hematology, University Medical Center Amsterdam, The Netherlands; Addenbrooke’s NHS Trust, Cambridge, UK; Dept Hematology/Oncology, Medical Center OLVG, Amsterdam, The Netherlands; North Hampshire Hospital, Basingstoke, UK; Leicester Royal Infirmary, Leicester, UK; Dept. of Haematology, Western General Hospital, Edinburgh, Scotland.